Current Studies

Current Studies

Get Involved

Current studies

These studies associated with the Enroll-HD platform are, or soon will be, recruiting participants. Most of these studies are recruiting people who are already participating in Enroll-HD.

If you are interested in getting involved in any of these studies, please visit the Study Sites page to find a site near you and contact the study coordinator listed for that site.

GET INVOLVED

Current Studies

If you are interested in getting involved in any of these studies, please visit the Study Sites page to find a location near you and contact the study coordinator listed.

Enroll-HD

Enroll-HD is the world’s largest observational study for Huntington’s disease families. It monitors how the disease appears and changes over time in different people in a real-world setting.

HDClarity

HDClarity is the largest ongoing study collecting cerebrospinal fluid (CSF) in HD.

HD Charge

HD Charge is a multi-site online survey of health economics and outcomes that is evaluating the indirect and out-of-pocket cost burden in people with HD and their companions.

imageClarity

imageClarity is a neuroimaging study that will generate a high-quality MRI dataset to help researchers identify imaging markers of disease progression, which can later be used to evaluate the effectiveness of novel treatments.

iMagemHTT

iMagemHTT is using two different brain imaging techniques - PET and MRI - to evaluate the ability of two new imaging ‘tracers’ to measure levels of mutant huntingtin in the brain.

iMarkHD

iMarkHD is an adaptive longitudinal PET and MRI study in HD assessing molecular, functional, and structural changes in the brain from several years before symptom onset to advanced stages.

LSA

The Later Stage Assessment (LSA) study is evaluating two common HD assessments that have been adapted for telephone interview by a clinician that will be completed on behalf of the patient by their caregiver to evaluate people in the mid- to later-stages of HD.

Enroll-HD

Enroll-HD is the world’s largest observational study for Huntington’s disease families. It monitors how the disease appears and changes over time in different people in a real-world setting.

HDClarity

HDClarity is the largest ongoing study collecting cerebrospinal fluid (CSF) in HD. The study is sponsored by University College London, UK (UCL) and is funded and supported by the CHDI Foundation.

HD Charge

HD Charge is a health economics and outcomes-focused, multi-site, single assessment, cross-sectional, online survey aimed to evaluate the indirect and out-pocket cost burden in people with Huntington’s and their companions. The study is funded by CHDI Foundation.

ImageClarity

imageClarity is a neuroimaging study that aims to generate a high-quality MRI dataset to help researchers identify imaging markers of disease progression, which can later be used to measure the effectiveness of novel treatments.

iMagemHTT

iMagemHTT is a research study that uses two different brain imaging techniques - positron emission tomography (PET) imaging and magnetic resonance (MR) - to test two new brain imaging ‘tracers’ to evaluate if they can be used to measure levels of mutant huntingtin - a specific form of the protein that accumulates in the brains of people with Huntington’s disease.

iMarkHD

iMarkHD is an adaptive, longitudinal positron emission tomography (PET) and magnetic resonance (MR) imaging study in Huntington’s disease that aims to assess molecular, functional, and structural changes in the brain from several years before symptom onset to later stages where more advanced symptoms are observed.

LSA

The Later Stage Assessment (LSA) study is investigating the utility and performance of two common HD assessments which have been adapted specifically for remote (telephone) administration, and are intended for use in evaluating individuals in the mid- to later-stages of HD. These assessments are performed by a clinician and completed on behalf of the patient by their caregiver.