Enroll-HD

Publications

Publications leveraging Enroll-HD data, biosamples, and/or infrastructure.

Publications

Enroll-HD is both a worldwide observational study and a clinical research platform supporting various studies and trials, with an overall objective to accelerate HD therapeutic development. Clinical data and biosamples collected in Enroll-HD and other HD studies are made available through the Enroll-HD platform to any verified researcher per the Clinical Data and Biosample Access Policy to extract as much knowledge as possible. As ever, we are enormously grateful to the thousands of participants and families around the world who selflessly give their time and energy, as well as to the dedicated staff at the clinical sites who make Enroll-HD possible.

When publishing their findings, researchers using these data and biosamples are expected to adhere to the Enroll-HD publication policy, including full acknowledgement of the individuals who contributed to the collection of the Enroll-HD data. The publications hosted here have all used the Enroll-HD datasets that are periodically made available and illustrate some of the areas of HD research that Enroll-HD is directly influencing.

If your publication that uses Enroll-HD data is not included in this gallery, or you know of a publication that should be included, then please let us know at info@chdifoundation.org.

Authors

Title

Journal

Ghosh S, Sun Z, Li Y, Cheng Y, Mohan A, Sampaio C, Hu J

An exploration of latent structure in observational Huntington's disease studies
AMIA Jt Summits Transl Sci Proc
Jul 26, 2017
2017 :92-102
PMID: 28815114
PMCID: 5543350

Walker T, Ghosh B, Kipps C

Assessing decline: visualising progression in Huntington's disease using a clinical dashboard with Enroll-HD data
J Huntingtons Dis
Jun 30, 2017
6 (2) :139-147
PMID: 28550266

Hervás D, Fornés-Ferrer V, Gómez-Escribano AP, Sequedo MD, Peiró C, Millán JM, Vázquez-Manrique RP

Metformin intake associates with better cognitive function in patients with Huntington's disease
PLoS One
Jun 20, 2017
12 (6) :e0179283
PMID: 28632780
PMCID: 5478119

Schultz JL, Kamholz JA, Moser DJ, Feely SM, Paulsen JS, Nopoulos PC

Substance abuse may hasten motor onset of Huntington disease: Evaluating the Enroll-HD database
Neurology
Feb 28, 2017
88 (9) :909-915
PMID: 28148631
PMCID: 5331869

Frich JC, Rae D, Roxburgh R, Miedzybrodzka ZH, Edmondson M, Pope EB, Goodman L, Haddad MS, Giuliano J, Nelson EC, Guttman M, Nance M

Health care delivery practices in Huntington's disease specialty clinics: an international survey
J Huntingtons Dis
Jul 01, 2016
5 (2) :207-213
PMID: 27372053
PMCID: 4942722

Landwehrmeyer GB, Fitzer-Attas CJ, Giuliano JD, Gonçalves N, Anderson KE, Cardoso F, Ferreira JJ, Mestre TA, Stout JC, Sampaio C

Data analytics from Enroll-HD, a global clinical research platform for Huntington's disease
Mov Disord Clin Pract
Jun 22, 2016
4 (2) :212-224
PMID: 30363395
PMCID: 6174428

Bettencourt C, Hensman-Moss D, Flower M, Wiethoff S, Brice A, Goizet C, Stevanin G, Koutsis G, Karadima G, Panas M, Yescas-Gómez P, García-Velázquez LE, Alonso-Vilatela ME, Lima M, Raposo M, Traynor B, Sweeney M, Wood N, Giunti P, SPATAX Network, Durr A, Holmans P, Houlden H, Tabrizi SJ, Jones L

DNA repair pathways underlie a common genetic mechanism modulating onset in polyglutamine diseases
Ann Neurol
Jun 01, 2016
79 (6) :983-90
PMID: 27044000
PMCID: 4914895

McNally G, Rickards H, Horton M, Craufurd D

Exploring the validity of the short version of the Problem Behaviours Assessment (PBA-s) for Huntington's disease: a Rasch analysis
J Huntingtons Dis
Sep 01, 2015
4 (4) :347-69
PMID: 26756591
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