June 2025: This Month in Huntington’s Disease Research
Welcome to your June roundup of the latest and greatest Huntington’s disease (HD) research, served up fresh and easy to digest! This month, we’ve got gene therapies revving up, brain wiring revealing surprising detours, and molecular firefighters missing in action. From emotional rollercoasters inside the brain to decoding irritability storms, June’s science brings us closer […]
Trouble on the Block: When the Neighborhood Loses Its Best Firefighter
Picture a quiet neighborhood. Things used to run smoothly here. Kids played outside, front yards were mowed, and the neurons — the longtime residents — looked out for one another. But lately, fires are breaking out. And worst of all? The neighborhood’s most important firefighter, PKD1, has stopped showing up. That metaphor details findings from […]
Spark ignited: first HD patient dosed in new Roche gene therapy trial
Spark Therapeutics, recently integrated into Roche Pharmaceuticals, has been working on an HD gene therapy. It’s delivered via a one-time brain surgery and is designed to lower levels of the huntingtin protein. A (very) small safety study has recently begun, and so far, one brave individual has received this experimental therapy, known as RG6662 (or […]
The latest volume of HD genetics research reveals new gems but also mysteries
The latest instalment in a series of big studies to understand the genetics of Huntington disease (HD) just hit the shelves. These studies have focused on how small changes in the genetic letters of a person with HD can impact when they develop symptoms of the disease. The previous instalments in this series have been […]
When a Short Fuse Becomes a Storm: Understanding Irritability in Huntington’s Disease
We all have days when we feel irritable, like when you’re stuck in traffic, or someone cuts in line at the grocery store. But for people living with Huntington’s disease (HD), irritability isn’t just a passing mood. It can feel like a thunderstorm that arrives suddenly, often without warning, and affects not only the person […]
Inside the Brain’s Theme Park: How Huntington’s Disease Disrupts the Emotion Coaster
Welcome to Brainland, the bustling, 24/7 theme park in your head. There’s Memory Maze, Logic Log Flume, and of course, the Emotion Coaster, where your brain races through tracks themed around happiness, sadness, and anger. However, for some people who carry the gene for Huntington’s disease (HD), some of these rides start acting up long […]
EN 
ES 
IT 
DE 
FR