Cracking the Case: How a Smartphone “Detective” is Helping Track Huntington’s Disease Progression
team of researchers from Roche and University College London (UCL) have developed a new clinical measure called the Huntington’s Disease Digital Motor Score (HDDMS). This score compiles data collected remotely using smartphones, to track certain signs and symptoms of Huntington’s disease (HD). This new technology helps collect rich datasets and could help reduce the number […]
Unsung Heroes: Could Glial Cells Treat Huntington’s Disease?
New research is challenging how we think about treating brain diseases, like Huntington’s disease (HD). A study from the lab of Dr. Steven Goldman shows that transplanting healthy early-stage support cells from humans into the brains of adult mice that model HD improves movement, memory, and even survival. But that’s not all — these cells, […]
Simon Says Stop: What a Children’s Game Can Teach Us About Early Huntington’s Disease
Do you remember playing “Simon Says” as a child? It was fun, silly, and surprisingly tricky. You had to listen carefully and only act when you heard “Simon says”. If you moved at the wrong time, you were out. It turns out that Simon Says isn’t just a playground game. It’s also a helpful way […]
Energy off balance: How Huntington’s disease influences the cell’s powerhouse
A recent study used miniature 3D brain models grown from stem cells to explore how the genetic change that causes Huntington’s disease (HD) might impact early brain development, before neurons even become neurons. What they found suggests that the tipping point that balances how cells mature may be off, and it could be because of […]
Peeking at huntingtin and learning from a PET study
A recent publication discusses a non-invasive way of measuring levels of expanded HTT protein in the brain, using an imaging tool called a PET tracer. The results were variable, but there’s still a lot to learn from the study as development of HTT tracers continues! Measuring Levels Of Huntingtin In The Brain One of the […]
June 2025: This Month in Huntington’s Disease Research
Welcome to your June roundup of the latest and greatest Huntington’s disease (HD) research, served up fresh and easy to digest! This month, we’ve got gene therapies revving up, brain wiring revealing surprising detours, and molecular firefighters missing in action. From emotional rollercoasters inside the brain to decoding irritability storms, June’s science brings us closer […]
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