The Girl at the End of the World: A Gratitude Day Reflection on the Place that Built Our Science

⏱️ 9 min read | This Gratitude Day, March 23rd, we celebrate the extraordinary partnership between HD families, scientists, and caregivers, and reflect on the place that built the science on which we all stand. Read more
Turning down mismatch repair genes slows Huntington’s repeat growth in human neurons

⏱️ 10 min read | In a human cellular system, scientists dialed back mismatch repair genes to reduce CAG expansion by up to 69%. This work is in its early days, but it shows promise for “anti-expansion” therapies that could be used to delay HD onset. Read more
Huntington’s Disease Therapeutics Conference 2026 – Day 3

⏱️ 29 min read | Day 3 of the HD Therapeutics Conference dives into breakthrough science, new tools and bold ideas that are pushing HD research toward better treatments. Read more
Huntington’s Disease Therapeutics Conference 2026 – Day 2

⏱️ 18 min read | HDBuzz is back with Day 2 of the 21st annual CHDI HD Therapeutics Conference in Palm Springs, CA. We heard about new techniques to zoom in on HD biology in extraordinary detail. Read more
Huntington’s Disease Therapeutics Conference 2026 – Day 1

⏱️ 33 min read | HDBuzz is at CHDI’s Huntington’s Disease Therapeutics Conference, ready to bring you live updates from the most recent research in the field. Get ready for some exciting science! Read more
Australia Opens The Door for SKY-0515: Skyhawk Seeks Provisional Approval for Its Oral HD Drug

⏱️ 8 min read | An oral Huntington’s disease drug is eligible for accelerated approval in Australia. This isn’t full approval yet, but it opens a faster path to potentially getting this once-daily pill to people with HD sooner. Read more