The Global Site Investigator Database for Huntington’s disease (GSID) is a tool maintained by CHDI Foundation, Inc (CHDI). It is designed to assist clinical sponsors of HD studies in identifying sites with appropriate resources for participating in specific studies and trials, support in silico feasibility analyses, assist with site start-up activities, and to enable assessment of eligibility of sites to participate in the Enroll-HD HD Clinical Trial Site Certification scheme.

GSID is populated by study sites and covers several core resource areas, including: General (containing information about the institution and HD clinic), Contacts, Trial and study experience, HD Population, Facilities and Procedures, Neuroimaging, and Approvals and Contracting.

GSID also contains separate study-specific feasibility questionnaires that may utilize and build on the information contained in the core sections.

Why should sites complete the GSID?

The aim of GSID is to create a comprehensive database of site capabilities; completion of GSID may provide your site with increased opportunities to participate in future research endeavours.
Sites are asked to complete questions in each of the core sections. This may take some time, but once complete, updates will only need to be made if anything changes at your site (an annual reminder to review details will be sent by the GSID managers), or if some specific additional information is required from you. For example, sites may be requested to complete additional sections of the GSID for study-specific feasibility (e.g., Enroll-HD 2.0; platform studies), depending on the study requirements.

Please note: completion of GSID is a requirement for all Enroll-HD sites, including sites that are interested in becoming an Enroll-HD site.

Who has access to the GSID?

Information in the GSID will be available directly to the Enroll-HD and CHDI study teams. Each site also has access to their own data. Industry and academic study and trial sponsors and investigators must apply for access to the GSID; such access is subject to Enroll-HD Governance Committee approval and must be for the purpose of identifying sites that have appropriate facilities, experience, and resources for a specific study or trial.

Further information

Enroll-HD sites:

We have recently transitioned the GSID to a new platform (Core GSID). If your site already has a GSID profile, relevant information will be migrated to the new Core GSID. Please contact your Enroll-HD Site Manager or LANCO if you have any questions. If your site does not have a GSID record, please send us a message via the Contact Form.

If you are having trouble accessing your GSID profile or have any questions, please contact gsid@enroll-hd.org.

Clinical study sponsors:

To discuss access to information contained in the GSID, please send us a message via the Contact Form.